Methods
Summary
Our aim is to determine whether retroviral sequences are being re-expressed in the aging human transcriptome and if their re-activation can lead to the appearance of alternative cryptic Transcription Start Sites (TSS). To verify this hypothesis we will take advantage of RNA-Seq/CAGE-Seq experiments derived from donors whose biological age is known. We plan to screen and reprocess from raw data hundreds of samples.
Protocols
This project has not yet shared any protocols.