The Cancer Cell Race

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Boston, Massachusetts
Open Access
$2,000
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About This Project

Cancer is a disease of cell proliferation and invasion. Proliferation leads to tumor growth, while invasion drives metastases, the cause of death in 90% of cancer patients. Today, chemotherapy tries to stop cancer proliferation, but no drugs aim at stopping cancer invasion. To set the foundations on which such drugs could be tested, we are organizing a World Race to find the fastest cancer cells, as worthy targets for refining emerging drugs.

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What is the context of this research?

Cancer is a disease of cell invasion as much as it is of cell proliferation.
Malignant cells that leave a tumor can form metastases and are responsible of 90% of deaths in cancer.
Yet, today all drugs target cancer proliferation and no drug aims at stopping their invasion.

What is the significance of this project?

Slowing down cancer cell migration could delay the formation of distant metastases and extend the life of patients with cancer.
Although not a cure...

What are the goals of the project?

We will find the fastest cancer cells,
assemble a library and assign reference values
standard for testing anti-motility compounds/drugs
identify common targets for refining these drugs.

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Meet the Team

Daniel Irimia
Daniel Irimia

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Harvard Medical School
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