- 1. Wood, Madeleine R., Elaine A. Yu, and Saurabh Mehta. 2017. “The Human Microbiome in the Fight Against Tuberculosis.” The American Journal of Tropical Medicine and Hygiene 96 (6): 1274–84.
- 2. Maji, A. , Misra, R. , Dhakan, D. B., Gupta, V. , Mahato, N. K., Saxena, R. , Mittal, P. , Thukral, N. , Sharma, E. , Singh, A. , Virmani, R. , Gaur, M. , Singh, H. , Hasija, Y. , Arora, G. , Agrawal, A. , Chaudhry, A. , Khurana, J. P., Sharma, V. K., Lal, R. and Singh, Y. (2018), Gut microbiome contributes to impairment of immunity in pulmonary tuberculosis patients by alteration of butyrate and propionate producers. Environ Microbiol, 20: 402-419. doi:10.1111/1462-2920.14015
About This Project
How important are microbiomes in the prevention and treatment of Tuberculosis? Using African buffalo as a model system
African buffalo are maintenance hosts for bovine TB, as they can carry the disease for years with minimal symptoms. However, when the disease spills over into other species (wild, domestic, or human), the consequences can be severe in terms of economy, ecology, and public health. This project will help us understand how commensal bacteria are related to nutrition and TB in African buffalo, and hopefully give clues to how the disease can be managed more effectively.
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