Karim Djebali

Karim Djebali

Feb 19, 2019

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About This Project

Necrotizing enterocolitis is a severe inflammatory gastrointestinal disease and is the leading cause of morbidity and mortality (30-50%) in preterm neonates. An altered newborn's gut microbiota plays a major role in this condition. We hypothesize that secreted factors from one probiotic, Bifidobacterium infantis, could exert anti-inflammatory effects in the newborn's intestine. These observations might lead to ways to prevent excessive intestinal inflammation causing necrotizing enterocolitis.


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