Melissa Wilson Sayres

Melissa Wilson Sayres

Tempe, AZ

Genomics, Evolution, and Bioinformatics, School of Life Sciences; Center for Evolution and Medicine, The Biodesign Institute Arizona State University

Assistant Professor

More

Published on May 11, 2018

Making a genome

Making a new genome is like putting together a meta-puzzle. First, we think about the genome, which in our Gila monster, is not just one long strand of DNA, but many strands of DNA (chromosomes). S...

Group 6 Copy 307
Published on Jan 30, 2017

Arizona's Adorable Monster featured at the Atlantic

Ed Yong wrote about our wonderful monsters for the Atlantic. Read here for more about these awesome critters: https://www.theatlantic.com/sc...Here is the photo, by Will Burgess/Reuters that accomp...

Group 6 Copy 108
Published on Oct 30, 2016

Collecting blood

Last time we talked about our most important collaborators, the Gila monsters (you can read that here). I'm excited to share some pictures of the blood they've kindly donated to our efforts to lear...

Group 6 Copy 55
Published on Sep 27, 2016

Meet the monsters

What are we collecting? For this project, we are collecting a small blood sample from six Gila monsters. Some of the blood will be used for DNA analysis and some for RNA analysis. After we collect ...

Group 6 Copy 99
Published on Apr 23, 2016

Gila monster genome on Arizona 3TV

Thank you so much to Jason Volentine for his story on the Gila monster genome on Arizona's 3TV news yesterday featuring Dale DeNardo and a little cameo from me! http://www.azfamily.com/story/317974...

Group 6 Copy 82
Published on Apr 20, 2016

Monster genome

The Gila monster was featured on this week's Ask a Biologist podcast. You can read the transcript or listen here: https://askabiologist.asu.edu/explore/monster-dna?...

Group 6 Copy 60
Published on Feb 16, 2017

Gila monster on Nat Geo

Dr. Dale DeNardo and the wonderful Gila monster were featured on Nat Geo:United States of AnimalsNat Geo Wildhttp://channel.nationalgeographic.com/wild/united-...First shown Friday, April 29, 2016 ...

Group 6 Copy 23
Published on Apr 15, 2016

RNA versus DNA

Our first stretch goal is to sequence RNA from blood of the same three males and females that we are sequencing DNA from. Typically the DNA in each of our cells is the same. That's why you can be i...

Group 6 Copy 134
Show more updates
Don't tell @gilamonsterasu, but we're actually looking into how we could do this.
Sep 27, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
Will do! Working on the next one. The summer is an odd time around here, but planning on more regular updates. Thank you for your enthusiasm and patience!
Sep 27, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
We collect a blood sample using a 1mL syringe, from the base of the tail.
Jun 30, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
Thank you very much, Matthew! Please do share this site (experiment.com/gilamonster) with anyone else you think might be interested.
Apr 17, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
I'm glad to know it is helpful! Please let me know if you have any questions you'd like addressed in posts here. :)
Apr 16, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
That is a fantastic idea!
Apr 16, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
Yay!!! Thank you!!
Apr 14, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
<high five!> Thank you!
Apr 14, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
Thank you! We've got a great group here at ASU!
Apr 14, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
Thank you!!
Apr 14, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
In total, what we are raising here is about 1/3 of what we'll need for the whole high quality genome, so we're hoping to have enough success to work on a stretch goal!
Apr 14, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
Dear Chad, Current estimates of the Gila monster genome place it around 3G, similar to a human genome. After extensive discussions with some sequencing cores, we are anticipating about 20X coverage of each of the 6 individuals. This should be more than sufficient for estimating sex-specific regions of the sex chromosomes, and good coverage for estimating diversity.
Apr 14, 2016
Gila monster genomics: conservation, venom, and treatments for Type-II diabetes
View comment
Show more comments