Tuberculosis (TB) infects more than 10 million people per year and kills 1.4 million. One of the main causes of death is treatment failure due to the existence of multidrug resistant strains of Mycobacterium tuberculosis, the pathogen responsible for TB. The present project aims to seek for antimicrobial peptides, a class of molecules produced by a variety of organisms, with activity against M. tuberculosis, to further use them in TB therapy.