249
0
0
Like?
Please wait...
About This Project
Insulin and exercise improves diabetes, AD and PD. In diabetes, resident immune cells (RICs) secrete inflammatory cytokines upon ingestion of fat deposits, inhibiting Akt signaling. Glial derived neurotrophic factor (GDNF) also activates Akt. Perhaps a similar mechanism occurs in the CNS, involving RIC exposure to alpha-synuclein aggregates. We will attempt to replicate this in vitro and characterize RIC inflammatory status, then expose neuronal lines to RIC and monitor Akt inhibition.
More Lab Notes From This Project
Browse Other Projects on Experiment
Related Projects
Dermatology AI Assistant to Empower Primary Care Providers in Zaatari Refugee Camp in Jordan
An AI-assisted dermatology tool for refugees, utilizing imaging and symptom questionnaires to improve diagnostic...
Which marine mammal eats the most microplastics?
Marine mammals, like dolphins, eat food contaminated by microplastic pollution, which could cause serious...
Can we find a low cost solution to store temperature sensitive enzymes in research?
Temperature-sensitive reagents are common in biology labs, and often need to be stored in expensive ultra...