Jason S Groshong

Jason S Groshong

Dec 28, 2021

Group 6 Copy 501
0
    Please wait...

    About This Project

    Insulin and exercise improves diabetes, AD and PD. In diabetes, resident immune cells (RICs) secrete inflammatory cytokines upon ingestion of fat deposits, inhibiting Akt signaling. Glial derived neurotrophic factor (GDNF) also activates Akt. Perhaps a similar mechanism occurs in the CNS, involving RIC exposure to alpha-synuclein aggregates. We will attempt to replicate this in vitro and characterize RIC inflammatory status, then expose neuronal lines to RIC and monitor Akt inhibition.

    More Lab Notes From This Project

    Blast off!

    Browse Other Projects on Experiment

    Related Projects

    Developing a low-cost, rapid diagnostic for urogenital Schistosomiasis infection

    We are developing a frugal diagnostic for urogenital schistosomiasis, a neglected tropical disease that...

    How does taking Ritalin affect depersonalization-derealization disorder patients?

    We are investigating Ritalin's role in alleviating symptoms of depersonalization-derealization (DPDR) disorder...

    Synthesis of a Kidney Cancer Drug

    We need to prepare a 75 mg sample of our anti-kidney cancer drug for testing. The sample was requested by...