Can ibuprofen, an anti-inflammatory drug, suppress or mitigate alcohol's toxic effects on the developing brain? By protecting against alcohol-induced neuroinflammation, ibuprofen is predicted to improve the deficits in behavior (e.g., hyperactivity) and cognition (e.g., poor memory) typically seen in individuals born with fetal alcohol spectrum disorder (FASD). This research, we hope, will galvanize new strategies for treating children and adults with FASD.