About This Project
NU iGEM is creating a delivery system for an innovative antibiotic method centered around CRISPR, a powerful gene editing tool. With CRISPR, researchers can design guide RNA to direct the protein Cas9 to cut out any gene from a cell. In our case, we will target antibiotic resistance genes, leaving pathogens defenseless. We want to harness the natural messenger properties of bacterial outer membrane vesicles (OMVs) to package Cas9 and deliver it to cells as a biological Trojan Horse.