Crystals Found! (Guarded optimism necessary!)
Our awesome crystallographers screened for crystals and found some! Though there are many steps that follow which need to go right for successful data, this is a hopeful first one!
About This Project
Some South American opossums have a blood protein (vWF) which has evolved resistance to snake venom. Our lab examines how three venom proteins interact and evolve with vWF. However, necessary data for one of these proteins, Aspercetin, are lacking. This project aims to sequence Aspercetin and obtain the crystal structure of vWF complexed with Aspercetin, to understand how this protein has evolved to target vWF, and how opossums have co-evolved to combat its deadly function.
More Lab Notes From This Project
Browse Other Projects on Experiment
Related Projects
Urban Pollination: sustain native bees & urban crops
Bee activity on our crop flowers is crucial to human food security, but bees are also declining around the...
Wormfree World - Finding New Cures
Hookworms affect the lives of more than 400,000,000 men, women and children around the world. The most effective...
Viral Causes of Lung Cancer
We have special access to blood specimens collected from more than 9,000 cancer free people. These individuals...
1 comment