Behind the Lab Bench: How we go from organoids to imaging.

Nov 13, 2020

444

Behind the Lab Bench: How we go from organoids to imaging. 
This past week we have been working on histology in order to examine the 
structure and morphology of our uterine organoids (generated from cell 
lines). You can check out part 1 and 2 of how we go from organoids
to imaging here

Here we embed our tissues (organoids) in wax, and section them super 
thin. We then collect them on a slides, and then they are ready for 
histological dyes and stains. There is something about sectioning these wax blocks that is very zen to me. It's almost meditative. 
Stay tuned for part 3 :)
-Tee

Teerawat, Jackeline, and 2 others like this.

0 comments

Join the conversation!Sign In

About This Project

Modeling Zika virus transmission from mother to child using uterine mini-organs

National Center for Genetic Engineering and BIotechnology (BIOTEC), Thailand

As of mid-2019, 87 countries have had or still have Zika cases, underlining the importance of this infectious disease. Zika virus can infect the uterus and later infect the infant during pregnancy, causing neurodevelopmental defects at birth. This study will model Zika infection in the lab using uterine mini-organs. We hypothesize that our specific antibodies can neutralize Zika virus in the uterus and thus prevent later transmission from pregnant mother to unborn child.