Oluwaseun Ajayi

I am Oluwaseun Ajayi, a bioanalytical chemist with a strong focus on enzyme biochemistry and natural product biosynthesis. Throughout my academic and research career, I have been driven by a deep curiosity about how living organisms produce complex molecules, particularly antibiotics, which have critical applications in medicine. My training in bioanalytical chemistry has equipped me with advanced skills in protein expression, purification, and spectroscopic analysis, enabling me to study the molecular details of enzyme function and cofactor interactions.

My current research centers on AprL, a pyridoxal phosphate (PLP)-dependent aminotransferase involved in the biosynthesis of apramycin, an important antibiotic. By investigating AprL’s expression, purification, and cofactor binding, I aim to uncover fundamental biochemical properties that could lead to engineering improved antibiotic pathways. This work has the potential to contribute to combating antibiotic resistance, one of the most pressing global health challenges.

I became interested in this field during my graduate studies when I recognized the power of combining analytical chemistry techniques with molecular biology to address real-world problems. I am passionate about bridging fundamental science with applied research, working at the interface of chemistry and biology to drive innovation.

Beyond the lab, I am committed to sharing my findings through conferences and publications, fostering collaborations that accelerate progress in antibiotic discovery. This project marks an important foundation in my research journey, where I seek not only to generate new scientific knowledge but also to contribute solutions that can improve human health worldwide.

May 2025