asatanowski

Ari Satanowski is a Postdoctoral Fellow at The Francis Crick Institute in London, where he has joined the Biodesign Lab lead by Erika DeBenedictis. He works on developing phage-assisted continuous evolution (PACE) methods for metabolic enzymes and sustainable bioproduction.

Ari earned his PhD at the Max Planck Society in Germany under the guidance of Prof. Tobias Erb and Dr. Arren Bar-Even. His PhD research focussed on the design and demonstration of new-to-nature metabolic pathways for utilization of CO2 and one-carbon compounds. Ari remains interested in the question how to engineer such pathways most effectively inside living microbes, and aims to apply rapid, high-throughput evolution techniques to speed up this development.

The project we propose here for the "Garden Grants" will tie in well with ongoing work at the Biodesign Lab, taking advantage of recent methods developed by Ari and other team members, including the directed evolution of biosensors and metabolic enzymes. Ari will be able to tap into the pool of instruments, genetic resources, and technical expertise available in the group, most importantly for phage- and robotics-assisted evolution (PRANCE) on an automated liquid handling platform.

Ari's previous Publications (Google Scholar)

February 2025