University of Southern California
Chief Medical Officer, Los Angeles County-University of Southern California Medical Center
I am the Chief Medical Officer at the Los Angeles County-University of Southern California (LAC+USC) Medical Center. I am also a Professor of Clinical Medicine and Associate Dean for Clinical Affairs at the Keck School of Medicine at USC. My NIH-funded research interests are diverse, ranging from basic immunology and vaccinology, to pure clinical and outcomes research, to process improvement work related to delivery of care, focusing on safety net hospitals. My laboratory research has focused on developing a vaccine that targets the bacterium Staphylococcus aureus and the fungus Candida; the vaccine is undergoing clinical development. I am currently working on the immunology, vaccinology, and host defense against highly resistant Gram negative bacilli, including Acinetobacter and carbapenem-resistant Enterobacteriaceae infections.
I have worked extensively with the Infectious Diseases Society of America (IDSA) to attempt to bring attention to the problems of increasing drug resistance and decreasing new antibiotics. My research regarding new drug development was a cornerstone of the IDSA’s white paper, Bad Bugs, No Drugs, and has been cited extensively in medical literature and on Capitol Hill. As a member and then co-chair of the IDSA’s Antimicrobial Availability Task Force (AATF), I first-authored numerous IDSA position papers and review articles relating to public policy of antibiotic resistance and antibiotic development. Finally, I am the author of Rising Plague, which I wrote to inform and educate the public about the crisis in antibiotic resistant infections and lack of antibiotic development.