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Can TFD100 restore NK cell immunity in cancer patients?
Our immune system recognizes cancers and under some circumstances, it controls or even eliminates tumors. Unfortunately, tumors can avoid immune surveillance and cancer metastasis can be accelerate...
TFD100 inhibits gal3-mediated apoptosis of cytotoxic T cells
Our immune system recognizes cancers and under some circumstances, it controls or even eliminates tumors. Unfortunately, tumors can avoid immune surveillance by stimulating immune inhibitory recept...
TFD100 blocks metastasis of prostate cancer cells in mice
Metastasis is the primary cause of death in cancer patients.Here we show TFD100 (a natural glycopeptide purified from Pacific cod) blocks metastasis of prostate cancer cells in mice.Since PC-3 (pro...
TFD100 inhibits interaction between tumor cell and endothelial cell
Metastasis (development of secondary malignant growth at a distance from a primary site of cancer) is the primary cause of death in cancer patients. For this multi-step metastatic process, malignan...
TFD100 inhibits angiogenesis
Development of new blood vessels (called angiogenesis) is essential step of cancer metastasis. Cancer cells get nutrients through these blood vessels and grow. Inhibition of angiogenesis would ther...
Increased epression of Thomsen-Friedenreich disaccharide (TFD) in prostate cancer tissues
Immunohistochemical analysis of prostate cancer tissues showed increased expression of TFD (Gal-beta1,3Gal) in advanced stages of prostate cancer (Stage II-IV) (see Figure). During cancer metastasi...