Shyam Sathyamoorthi completed a B.S. degree in Cell and Molecular Biology with a minor in Chemistry at Tulane University, New Orleans, Louisiana, where he worked in the labs of Professor Ken Muneoka and Professor Robert A. Pascal, Jr. He then completed a PhD in chemistry at Stanford University under the guidance of Professor Richard N. Zare (2018) as well as a Doctor of Medicine degree at the Stanford University School of Medicine (2019). In July 2019, he started his independent career as an assistant professor in the Department of Medicinal Chemistry at the University of Kansas, Lawrence, KS, USA. He was promoted to associate professor (with tenure) in 2024.
