Group 6 Copy 46
0
References
  • 1. Adams, BD, Anastasiadou, E, Esteller, M, He, L, & Slack, FJ. (2015). The Inescapable Influence of Noncoding RNAs in Cancer. Cancer Research, 75(24), 5206-5210. DOI:10.1158/0008-5472.can-15-1989
  • 2. Gonzalez-Martin, A, Adams, BD, Lai, M, Shepherd, J, Salvador-Bernaldez, M, Salvador, JM, Lu, J, Nemazee, D, Xiao, C. (2016). The microRNA miR-148a functions as a critical regulator of B cell tolerance and autoimmunity. Nature Immunology, 17(4), 433-440. DOI: 10.1038/ni.3385
  • 3. Roberts, NA, Adams, BD, McCarthy, NI, Tooze, RM, Parnell, SM, Anderson, G, … Horsley, V. (2017). Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity. The Journal of Immunology, 199(4), 1250–1260. doi:10.4049/jimmunol.1600941
  • 4. Singh, T, and Adams, BD. (2017). The Regulatory Role of miRNAs on VDR in Breast Cancer. Transcription, 8(4), 232–241. DOI:10.1080/21541264.2017.1317695
  • 5. Adams, BD, Wali, VB, Cheng, CJ, Inukai, S, Booth, CJ, Agarwal, S, Rimm, DL, Győrffy, B, Santarpia, L, Pusztai, L, Saltzman, WM, and Slack FJ. (2016) miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple Negative Breast Cancer. Cancer Research, 76(4), 927-939. DOI: 10.1158/0008-5472.CAN-15-2321
  • 6. Adams, BD, Parsons, C, and Slack, FJ. (2016). The Tumor-Suppressive and Potential Therapeutic Functions of miR-34a in Epithelial Carcinomas. Expert Opinion Therapeutic Targets, 20(6), 737-753. DOI: 10.1517/14728222.2016.1114102
  • 7. Metheetrairut, C, Adams, BD, Nallur, S, Weidhaas, J, and Slack, FJ. (2016) cel-mir-237 and its Homologue, hsa-miR-125b, Modulate the Cellular Response to Ionizing Radiation. Oncogene, 36(4), 512-524. DOI: 10.1038/onc.2016.222
  • 8. Adams, BD, Parsons, C, Walker, L, Zhang, WC, and Slack, FJ. (2017) Targeting Noncoding RNAs in Disease. Journal Clinical Investigation, 127(3), 761-771. DOI: 10.1172/JCI84424
  • 9. Chua FY, and Adams BD. (2017). Androgen Receptor and miR-206 Regulation in Prostate Cancer. Transcription, e1322668. DOI: 10.1080/21541264.2017.1322668
    Please wait...

    About This Project

    The treatments available for glioblastoma multiform (GBM) patients provide a minimal survival benefit, and novel methodologies to detect and treat GBM are needed. This project focuses on a gene product called noncoding RNA, a molecule that regulates the expression of tumor-causing genes at the RNA level. The Institute identified novel RNA transcripts detectable in human cancer. We will determine the consequences when cells lose these transcripts and will develop noncoding RNA biomarkers for GBM.

    Blast off!

    Browse Other Projects on Experiment

    Related Projects

    The Secret Life of Parrots: decoding vocal babbling in wild parrot chicks

    I’m studying the first observable behavior of wild parrot babbling inside the nest. Similar to infants...

    How do temperature and competition affect true fruit flies and their natural enemies?

    True fruit flies (Tephritidae) have an economic impact of hundreds of millions (USD) in the USA alone. They...

    Back to the Basics of Synthetic Biology

    Need a to get back to the basics on what synthetic biology is? Check out our Lab Notes section below...

    Backer Badge Funded