About This Project
Microbiology Laboratory, San Gerardo Hospital, Monza, Italy
Clostridium difficile infection is a toxin-mediated bacterial infection responsible for 500,000 infections and 30,000 deaths in the US alone. Clostridium difficile virulence and mortality rates increased 5-fold in the last 15 years. In the laboratory, we discovered that the major protein of the egg white, albumin, protects cells from toxin-induced death. The goal of is to test whether albumin administration can reduce the mortality rate associated with Clostridium difficile infection in vivo.