About This Project
Identifying the genes necessary to regenerate an injured brain - insights from a basal chordate, Ciona intestinalis
Only a few regions of the mammalian brain are capable of replacement by neural stem cells, therefore it is important to develop therapies for repairing damaged brains. In striking contrast, Ciona has the capacity to completely regenerate its brain based on the contributions of pluripotent stem cells. As Ciona is a basal chordate that is the closest living relative of vertebrates, information obtained in this model may be relevant to vertebrate brain regeneration.