Parthasarathy Chandrakesan

I have a broad background in Cancer and stem cell biology, gastroenterology and endocrinology with extensive training and experience in molecular and cellular biology and animal models relevant to the background knowledge. I carried out research investigating the role of NF-kB/b-catenin/Notch signaling during intestinal crypt hyperplasia and neoplasia. I expanded my research to include the isolation, purification and characterization of intestinal, pancreatic, hepatic, colon and breast stem cells. We have established a tumor stem cell marker, DCLK1, and found it to be upregulated in many cancers. Recently I have established the functional importance of DCLK1 as a protein enhances breast tumorigenesis. My research experience and scientific expertise in the field of stem cell and bresast cancer biology have prepared me to successfully carry out this research.

October 2013