Ithaka
Kavli Institute for Nanoscale Science at Cornell University, USA.
PhD, Biochemist and Programmer
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I performed my Master in Medical Biochemistry in 2007. Thereafter I started my Ph.D. studies at the Radboud Institute for Molecular Life Sciences in Nijmegen, The Netherlands, where I completed my experimental PhD thesis on the impact of cell surface glycosylation on tumor cell migration and invasion in vitro and in vivo. In 2013, I received the prestigious Roche Postdoc Fellowship (RPF) from F. Hoffmann-La Roche Ltd, Basel, Switzerland, and developed a GFP complementation assay to study the transport of functional cell-penetrating peptides (CPPs) from the cell surface to the cytosol with focus on endosomal release. Based on these findings I co-developed and published the peptide prediction software application "Peptify" for instant identification of amino acid combinations that can penetrate the cell membranes. Furthermore, I studied the influence of cell surface glycosylation on the uptake of CPPs. In February 2017 I received the KIC Postdoc Fellowship from the Kavli Institute for Nanoscale Science at Cornell University, USA.
My research was published in numerous high ranking journals and presented on national and international conferences.
I am involved in the development of R codes, which I have co-founded. Furthermore, I am involved in the development of Frapbot, a free-of-charge open source software web application written in R, which provides manual and automated analyses of fluorescence recovery after photobleaching (FRAP) datasets for molecular mobility studies. Frapbot has just been published. Both projects are part of the Vaionex Corporation, a young datascience & biotech startup I have co-founded in 2016.
Find more information about me and my research here.
August 2017