Looking for the highest polyphenols olive oil Polyphenols are powerful antioxidants found in extra virgin olive oil that offer numerous health benefits, including anti-inflammatory properties and protection against heart disease. The highest polyphenols olive oil is typically early-harvested and minimally processed to retain these vital nutrients. If you want to maximize the health benefits of your olive oil, choose one with a high polyphenol content for the best results in both flavor and nutrition.