Kevin Shen

Kevin Shen

University of Waterloo

Researcher, Project Co-lead

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Haven't backed any projects yet! 

Reply to:Erin WilsonErin Wilson
They are related because of scATAC-seq. Please feel free to refer to the comment in the solution statement.
Nov 14, 2023
Project: Cultivated Seafood: Single-Cell Multiomic Analysis of Killifish for...
Reply to:Erin WilsonErin Wilson
It would be more of the latter - identifying functions/processes of cell types. The clustering of cell types could be done without GO terms, so we won’t need to feed these GO terms back into cell type classification, though they can serve as a useful sanity check in that analysis! The GO term fun...more
Nov 14, 2023
Project: Cultivated Seafood: Single-Cell Multiomic Analysis of Killifish for...
Reply to:Erin WilsonErin Wilson
Feel free to check the reply in the solution statement for the answer to this question.
Nov 14, 2023
Project: Cultivated Seafood: Single-Cell Multiomic Analysis of Killifish for...
Reply to:Erin WilsonErin Wilson
We think so too! The scGPT model we found was trained on a combined/integrated dataset of 33 million human cells. The only two existing papers we have found that have generated single cell data in a cultivated meat context total ~50k cells (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE21...more
Nov 14, 2023
Project: Cultivated Seafood: Single-Cell Multiomic Analysis of Killifish for...
Reply to:Breanna DuffyBreanna Duffy
Yup! There are reference genomes available for our next three species. 1) Cyprinus carpio (Common Carp): https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_018340385.1/ Killifish is similar to carp, and as such carp is the species we expect to gain the most translatable insights from through our in...more
Nov 14, 2023
Project: Cultivated Seafood: Single-Cell Multiomic Analysis of Killifish for...