Ray Grogan

rgrogan

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Thanks for taking on a very difficult but important project. Maybe maybeI Don Ingber's team at Wyss could make you an organ-on-a-chip that could secrete your protein into a solution in which it would not fold up. Then you could inject changes into the solution - polarity, etc. and "watch" it move.
Aug 09, 2017
Unraveling the mystery of TDP-43, a versatile protein involved in several Neurodegenerative disorders
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Not that you need any more variables to keep track of at this stage, but have you looked for effects on the next generation? For example, in humans the nutrient folic acid seems to prevent birth defects if taken in the first critical weeks of pregnancy. There are about 15 nutrients that may have similar effects. So maybe in your cool fish something the parents take could affect the lifespan of their offspring. Anyway, great experiments, logic, and pix. Holler if you want a Hawaiian taro plant for your aquarium.
Nov 16, 2014
Do dietary supplements extend lifespan and prevent brain disease?
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