About This Project

I´m developing a new algorithm for a 3D bioprinter what permit to print customized 3D printed bone scaffolds. One of the most difficult technical challenge is to be able to print at the same time PLLA (biologic plastic) and bone proteins (organic material). This is the most important evidence to confirm in order to be able to launch a more ambitious project. I need to support with experimental evidences all theory.

Ask the Scientists

What is the context of this research?

The biocompatibility profiles of synthetic substances (biomaterials) used for the replacement or augmentation of biological tissues have always been a critical concern within the health care disciplines. Special circumstances are associated with bone implant prosthetic reconstruction of the oral-maxillofacial areas because the devices extend from the mouth, across the protective epithelial zones, and onto or into the underlying bone. The functional aspects of use also include the transfer of force from the occlusal surfaces of the teeth through the crown and bridge and neck-connector region of the implant into the implant for interfacial transfer to the supporting soft and hard tissues. This situation represents a very complex series of chemical and mechanical environmental conditions.

What is the significance of this project?

The clinical goal is to create a suitable environment in which the natural biologic potential for functional regeneration can be maximized. Important factors involved in the creation of a suitable environment for implant placement and successful bone consolidation will include biomechanical stability, prevention of acute inflammation resulting from bacterial infections, creating of a regenerative space around the implant. The business goal is to obtain a new certified medical product, patented, that will allow us to become the world leaders in the field of implants and bone regeneration in the dental market

What are the goals of the project?

At this early stage of the project, I want to get scientific evidence of the developed algorithm allow organic survivance after 3d manufacturing process. This is an important topic needed to be able to launch the bigger and ambitious project about the specific customized device for guided bone regeneration.