Michael Scolaro

Michael Scolaro

Oct 11, 2017

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Curcumin Root

Curcumin: Anti-Inflammatory Activities

Evidence of anti-inflammatory activity and safety of curcumin in laboratory and human studies:

Studies have identified a number of different molecules involved in inflammation that are inhibited by curcumin including phospholipase, lipooxygenase, cyclooxygenase 2, leukotrienes, thromboxane, prostaglandins, nitric oxide, collagenase, elastase, hyaluronidase, monocyte chemoattractant protein-1 (MCP-1), interferon-inducible protein, tumor necrosis factor (TNF), and interleukin-12 (IL-12).

Safety and anti-inflammatory activity of curcumin: a ... - NCBI - NIH https://www.ncbi.nlm.nih.gov/pubmed/12676044J Altern Complement Med. 2003 Feb;9(1):161-8. Safety and anti-inflammatory activity of curcumin: a component of tumeric (Curcuma longa). Chainani-Wu N(1).

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About This Project

We have invented a Nanocarrier that targets the Immune System to deliver Curcumin, an anti-inflammatory agent, to the brain for the treatment of neurodegenerative diseases, such as Chronic Traumatic Encephalopathy.

Our preclinical study at Charles River Labs and the U. of Arizona, is being conducted to establish proof of effective nanocarrier delivery of Curcumin to the cells of the brain damaged by repeated traumatic athletic injuries to the head.

Blast off!

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