Jan 20, 2016
What we found in the lab. In the right picture you can see how albumin administration allow infected cells to survive the infection... This effect has never been demonstrated before. We would test this effect on organisms to see if this can reduce Clostridium difficile related mortality.
Antonio, Marco L. Bianchini, and 4 others like this.
Clostridium difficile infection is a toxin-mediated bacterial infection responsible for 500,000 infections and 30,000 deaths in the US alone. Clostridium difficile virulence and mortality rates increased 5-fold in the last 15 years. In the laboratory, we discovered that the major protein of the egg white, albumin, protects cells from toxin-induced death. The goal of is to test whether albumin administration can reduce the mortality rate associated with Clostridium difficile infection in vivo.
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