Jesse Collins

jeswcollins

Brookline, MA

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You don't agree with some of my opinions? ;) Thanks for your help Jon!
Nov 20, 2014
Statistical Mechanics for (some of) Life's Puzzles
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Thanks Oscar for such great questions! I hope you don't mind if I respond with more questions than answers :). First, for all I know, yes, the ribosome could be more stable after a rearrangement, but I doubt it would still perform its function of making more proteins. Are the most stable arrangements of individual proteins (their 3-D folds) and of protein complexes also their functional states? How does the most stable fold of a single protein depend on the proteins around it? Could a protein or protein complex spend a very long time in one metastable state, even though it is not the most stable? My theoretical work doesn't solve these questions, but I think it provides a framework that could lead to answers.
Nov 20, 2014
Statistical Mechanics for (some of) Life's Puzzles
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