Searching for Genetic Clues in Autism with Family Trio Sequencing

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StartCodon
La Jolla, California
BiologyMedicine
Open Access
DOI: 10.18258/4764
$2,300
Raised of $1,750 Goal
131%
Funded on 5/01/15
Successfully Funded
  • $2,300
    pledged
  • 131%
    funded
  • Funded
    on 5/01/15

Discussion

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  • Don Pickard
    Don Pickard
    Prove it bro.
    May 07, 2018
  • Dana Brenneman
    Dana BrennemanBacker
    How exciting!
    Apr 09, 2015
  • KT Pickard
    KT PickardResearcher
    Thank you, Dana!
    Apr 09, 2015
  • Oliver Aalami
    Oliver AalamiBacker
    Awesome project. Would love to get feedback on results!
    Mar 31, 2015
  • KT Pickard
    KT PickardResearcher
    Oliver, all of our backers will receive a copy of the paper. Thank you for your support!
    Apr 01, 2015
  • Sheila Wang
    Sheila WangBacker
    Great idea! Hope you have more breakthroughs.
    Mar 31, 2015
  • KT Pickard
    KT PickardResearcher
    Thank you, Sheila!
    Apr 01, 2015
  • Adam K
    Adam KBacker
    This will be a really cool study! Good luck!
    Mar 29, 2015
  • KT Pickard
    KT PickardResearcher
    Adam, thank you for your support!
    Mar 29, 2015
  • Raymond McCauley
    Raymond McCauleyBacker
    Woohoo!
    Mar 26, 2015
  • KT Pickard
    KT PickardResearcher
    Thank you for your support & also for the RT on Twitter!
    Mar 29, 2015
  • Pietro
    PietroBacker
    Hi KT, great project. Pleased to see that pledges have already reached 100% of your initial budget. I was wondering if at this stage you could say something more about how you would use any additional $$ that might come in. Thanks!
    Mar 25, 2015
  • KT Pickard
    KT PickardResearcher
    Hi Pietro, I will be adding a stretch goal shortly. Additional $$ will be used for publication fees in an open access journal. Keep your eye out for an updated Lab Note!
    Mar 25, 2015
  • Pietro
    PietroBacker
    Great! I totally agree that your research should be published open access (although PeerJ will charge $100 per author only, and Plos one $1350 per paper). Also consider uploading draft to a pre-print server (e.g. biorxiv): I've seen very interesting discussion develop from there.Just putting this on the table: cheaper publishing might allow a second 'trio' to be sequenced(?)
    Mar 26, 2015
  • KT Pickard
    KT PickardResearcher
    When I first wrote about open access publishing in 2012, I found the average publishing cost was $2,500 (see http://www.jopm.org/opinion/commentary/2012/07/18/the-impact-of-open-access-and-social-media-on-scientific-research/). Also, I have found that getting accepted to PeerJ or PLOS ONE can be very challenging for non-academic researchers. If we are accepted to a lower-cost, peer-reviewed open access journal, we will use the additional funds for more analysis time using VarSeq. Thank you for your comments!
    Mar 28, 2015
  • KT8
    KT8
    I think you can request for a fee waiver in PlosOne. Just explain your situation (which I think is very valid) and they might grant you a waiver.
    Jun 30, 2015
  • KT Pickard
    KT PickardResearcher
    Thank you, Kt8, I didn't know about the possibility of a fee waiver in PLOS ONE. Our preliminary findings are encouraging (see this Lab Note: https://experiment.com/u/dIeFDw). If they hold up, we will publish results later this year.
    Jun 30, 2015
  • Oscar Jasklowski
    Oscar JasklowskiBacker
    Awesome work, KT! Do you have any good reading to get up to speed on family trio sequencing? I'm really curious about 1) how it's been used, and 2) how the insights differ from sequencing when you look at a bigger population. Any resources you have would be much appreciated!!
    Mar 24, 2015
  • KT Pickard
    KT PickardResearcher
    Hi Oscar, I just added a Lab Note that introduces family trio sequencing: https://experiment.com/u/oSMmA
    Apr 18, 2015
  • Georgia Cox
    Georgia CoxBacker
    As a family therapist, I am very excited by your project and inspired by your family's collaboration. Looking forward to following your research.
    Mar 24, 2015
  • KT Pickard
    KT PickardResearcher
    Thank you, Georgia!
    Mar 25, 2015
  • Cindy Wu
    Cindy WuBacker
    Love what you're working on! Wishing you all the best 🚀
    Mar 24, 2015
  • KT Pickard
    KT PickardResearcher
    You can read more about our first donation here: https://experiment.com/u/GMg2zA
    Mar 24, 2015