Patrick Frost, PhD

Patrick Frost, PhD

Jan 23, 2016

Group 6 Copy 44
0
Please wait...

About This Project

BBRI and Los Angeles VA Medical Center

Multiple myeloma (MM) is a cancer of the bone marrow made up of plasma cells (a type of antibody-producing white blood cells). Low oxygen levels (called hypoxia) in the bone marrow increases gene expression in MM tumor cells as part of an adaptive survival response. We are targeting this hypoxic response with an experimental drug that blocks expression of these genes to ask if this molecule kills MM in the bone marrow. This is a novel approach to treat MM, an incurable disease.

Blast off!

Browse Other Projects on Experiment

Related Projects

Can we restore the Chilean "espinal" with guanacos?

Guanacos, the wild cousins of llamas, lived throughout Chile until about 500 years ago. Central Chile is a...

Are Greek lizards adapting to live with humans?

Traditional stone walls in Greece host high densities of lizards that look and perform differently from lizards...

Backer Badge Funded