Patrick Frost, PhD

Patrick Frost, PhD

Jan 23, 2016

Group 6 Copy 51
0
Please wait...

About This Project

BBRI and Los Angeles VA Medical Center

Multiple myeloma (MM) is a cancer of the bone marrow made up of plasma cells (a type of antibody-producing white blood cells). Low oxygen levels (called hypoxia) in the bone marrow increases gene expression in MM tumor cells as part of an adaptive survival response. We are targeting this hypoxic response with an experimental drug that blocks expression of these genes to ask if this molecule kills MM in the bone marrow. This is a novel approach to treat MM, an incurable disease.

Blast off!

Browse Other Projects on Experiment

Related Projects

An initial exploration of in-situ underwater genetic sequencing

Our goal is to adapt portable genome sequencing technology for high-pressure, underwater environments. Currently...

Squid in Space: Symbiosis and Innate Immunity

Astronauts experience dysregulated immune function in space that may be related to their microbial communities...

How do sponges influence the availability of nutrients on coral reefs?

Sponges are nature's filtration systems; they can filter up to 50,000 times their own volume in a day. Changes...

Backer Badge Funded