Patrick Frost, PhD

Patrick Frost, PhD

May 05, 2016

Group 6 Copy 57
0
Please wait...

About This Project

BBRI and Los Angeles VA Medical Center

Multiple myeloma (MM) is a cancer of the bone marrow made up of plasma cells (a type of antibody-producing white blood cells). Low oxygen levels (called hypoxia) in the bone marrow increases gene expression in MM tumor cells as part of an adaptive survival response. We are targeting this hypoxic response with an experimental drug that blocks expression of these genes to ask if this molecule kills MM in the bone marrow. This is a novel approach to treat MM, an incurable disease.

Blast off!

Browse Other Projects on Experiment

Related Projects

Does insecticide exposure affect solitary bee nesting behavior?

Alfalfa leafcutter bees (ALBs) are important crop pollinators that nest in aboveground cavities (e.g. straws...

Can we trick cyanobacteria into growing faster?

Cyanobacteria are photosynthetic organisms that can be used to produce liquid biofuels. One of the biggest...

Conservation Genetics of the Endangered Seychelles Magpie-Robin (Copsychus sechellarum)

My research concerns the population genetics of the Seychelles Magpie Robin. This species is listed as...

Backer Badge Funded