Patrick Frost, PhD

Patrick Frost, PhD

Feb 10, 2016

Group 6 Copy 64
2
Please wait...

About This Project

BBRI and Los Angeles VA Medical Center

Multiple myeloma (MM) is a cancer of the bone marrow made up of plasma cells (a type of antibody-producing white blood cells). Low oxygen levels (called hypoxia) in the bone marrow increases gene expression in MM tumor cells as part of an adaptive survival response. We are targeting this hypoxic response with an experimental drug that blocks expression of these genes to ask if this molecule kills MM in the bone marrow. This is a novel approach to treat MM, an incurable disease.

Blast off!

Browse Other Projects on Experiment

Related Projects

Do turtles have enough variation in adaptive genes to keep pace with climate change?

Climate change is expected to have impacts on biodiversity worldwide. Many species will be faced with a choice...

Micrographic study of thylacine hair (Thylacinus cynocephalus)

Existing papers describing the hair structure of the thylacine (also known as Tasmanian tiger, Thylacinus cynocephalus...

Backer Badge Funded