Cierra N. Sharp

Cierra N. Sharp

Aug 15, 2016

Group 6 Copy 29
-1
    Please wait...

    About This Project

    A major dose-limiting toxicity of some chemotherapeutics (like cisplatin) is nephrotoxicity, leading to acute kidney injury (AKI) in 30% of patients. The aim of my project is to develop a mouse model that recapitulates the dosing regimen humans receive in order to develop and test novel renoprotective agents. This is important as there are no therapeutic interventions for cisplatin-induced AKI, and no long-term studies on kidney function have been performed in mice treated with cisplatin.

    Blast off!

    Browse Other Projects on Experiment

    Related Projects

    A Bird's-eye View of Frog Habitats: Using a Drone to Survey Wetlands

    I study vulnerable frog species that inhabit human-constructed wetlands in the Grand River Grasslands of...

    Hot Metal Switch: Synthetic In Vitro Gene Circuit for the Detection of Metal Ions

    Drinking water contaminated by metals, most notably lead, poses health risks to children and adults alike...

    Performance-enhancing substances: How do male black widows use chemical cues to gain a competitive advantage?

    For a male black widow spider, life is a series of deadly challenges. He must first make a dangerous...

    Backer Badge Funded