Cierra N. Sharp

Cierra N. Sharp

Aug 15, 2016

Group 6 Copy 51
-3
    Please wait...

    About This Project

    A major dose-limiting toxicity of some chemotherapeutics (like cisplatin) is nephrotoxicity, leading to acute kidney injury (AKI) in 30% of patients. The aim of my project is to develop a mouse model that recapitulates the dosing regimen humans receive in order to develop and test novel renoprotective agents. This is important as there are no therapeutic interventions for cisplatin-induced AKI, and no long-term studies on kidney function have been performed in mice treated with cisplatin.

    Blast off!

    Browse Other Projects on Experiment

    Related Projects

    Identification and optimization of silica- and silicate-degrading enzymes for atmospheric CO2 removal

    Rock weathering is a process whereby atmospheric CO2 reacts with silicate minerals, promoting formation...

    Searching for new deep sea brittle star species in museum specimens

    JP / EN The deep sea brittle star or Asteronyx loveni collections at the Muséum national d'Histoire naturelle...

    The Ideal Molecular Barcode for Identifying Freshwater Green Algae (Chlorophyceae)

    The aim of this research is to find and test gene regions in the genome of freshwater green algae which...

    Backer Badge Funded