About This Project
A major dose-limiting toxicity of some chemotherapeutics (like cisplatin) is nephrotoxicity, leading to acute kidney injury (AKI) in 30% of patients. The aim of my project is to develop a mouse model that recapitulates the dosing regimen humans receive in order to develop and test novel renoprotective agents. This is important as there are no therapeutic interventions for cisplatin-induced AKI, and no long-term studies on kidney function have been performed in mice treated with cisplatin.
Browse Other Projects on Experiment
Who's up there? Effects of land use on canopy plants in cloud forests and pastures of Monteverde, Costa Rica
Epiphytes grow in the canopy of trees, deriving support from their hosts, but getting water and nutrients...