Cierra N. Sharp

Cierra N. Sharp

Aug 16, 2016

Group 6 Copy 41
-3
    Please wait...

    About This Project

    A major dose-limiting toxicity of some chemotherapeutics (like cisplatin) is nephrotoxicity, leading to acute kidney injury (AKI) in 30% of patients. The aim of my project is to develop a mouse model that recapitulates the dosing regimen humans receive in order to develop and test novel renoprotective agents. This is important as there are no therapeutic interventions for cisplatin-induced AKI, and no long-term studies on kidney function have been performed in mice treated with cisplatin.

    Blast off!

    Browse Other Projects on Experiment

    Related Projects

    Increasing the bioavailability of carbohydrates through the interface of mycology and fermentation

    Due to increasing reliance on grain as a source of carbohydrates, shortages can occur if supply is interrupted...

    What is the known diversity of Somali waters?

    During Somalia’s 30-year-long civil war, my country lost many of our marine scientists. Now, Somalia lacks...

    Mapping the potential for UK universities to become research and teaching hubs for cellular agriculture

    Realising large scale production of cultured meat will need a workforce with a range of skills in areas...

    Backer Badge Funded