Cierra N. Sharp

Cierra N. Sharp

Jun 01, 2016

Group 6 Copy 59
0
    Please wait...

    About This Project

    A major dose-limiting toxicity of some chemotherapeutics (like cisplatin) is nephrotoxicity, leading to acute kidney injury (AKI) in 30% of patients. The aim of my project is to develop a mouse model that recapitulates the dosing regimen humans receive in order to develop and test novel renoprotective agents. This is important as there are no therapeutic interventions for cisplatin-induced AKI, and no long-term studies on kidney function have been performed in mice treated with cisplatin.

    Blast off!

    Browse Other Projects on Experiment

    Related Projects

    Are Costa Rican salamanders susceptible to Batrachochytrium salamandrivorans?

    The emergent fungal pathogen, Batrachochytrium salamandrivorans (Bsal), poses a significant threat to global...

    Beyond conservation concern: monk parakeets hold clues about human influences on evolutionary processes

    Parrots are the most threatened major group of birds, with many wild populations declining in response to logging...

    Backer Badge Funded