researcher
Daniel M. Ibrahim

Daniel M. Ibrahim

Berlin, Germany

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Published on Sep 11, 2015

Sequencing the LilBubome - Video Diary Pt. 1

Hi All,Despite the long silence, Daniel, Dario and I have been busy working on the LilBUBome, and we’ll be releasing more info in the next few weeks. As we reported last time, we had extracted high...

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Published on Jun 30, 2015

Leslie was here!

Hi All,we have been busy in the last weeks with a bunch of background work (mainly thinking about how to document our sequencing effort in a way that you get the most of it) and also catching up wi...

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Published on May 24, 2015

A rush and a push and then let the science begin!!

Hi All,On Tuesday we met our target and we're still thrilled about all the support we've received so far. Thank you, Merci, Gracias und Dankeschön, again and again!!!On Wednesday we set our new - v...

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Published on May 18, 2015

We're still answering a reddit AMA!

IT IS HERE: http://www.reddit.com/r/IAmA/comments/36dmfm/were_the_lilbubome_team_sequencing_the_genome_of/Hi everyone,this is just a brief note to tell you that we'll be doing a reddit Ask Me Anyth...

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Published on May 12, 2015

Ask an Expert - Prof. Uwe Kornak on BUB, Osteopetrosis, and Genetics.

Hi All,as we wrote in our project description, we are connected with experts in cat genetics and bone disorders to back us up on all the expert knowledge that we don't have. Together with them we t...

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Published on May 05, 2015

Congratulations! It's a Hemingway

Hi All,Last week Daniel was busy in the lab, doing a first experiment for the LilBUBome. And as we briefly posted yesterday: he found something really cool! We actually just wanted to test whether ...

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Published on May 04, 2015

OMFG! WTF?

Hi everybody,we got the results from sequencing and I think this project just went from pretty cool to frickin' awesome!1!!!We need to double check a few things and prepare a proper post but for th...

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Published on May 02, 2015

NerdTalk

OK people. We wanted to let you know how things sound and feel like in the lab. So this one is for those of you who are interested, have a little more background knowledge, or are scientists. Thes...

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Published on Apr 28, 2015

HOW TO FIND A MUTATION? - OF NEEDLES AND HAYSTACKS

Finding a disease-causing mutation is like finding a needle in a haystack (veeeery popular analogy amongst human geneticists) . Or rather like finding one needle in hundreds of haystacks. As in: it...

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This is a mega-mega cool project. I hope you make it and I'm excited for the results!!! Best of luck
Feb 12, 2016
Sequencing the genomes of all known kākāpō
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Really hope you get funded! I'll keep my fingers crossed. d
Jan 09, 2016
Investigating how green crab extinction affects seabed ecosystems in Irish waters
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Hi Nancy, I very much share your opinion and all cats I ever had were adopted from the previous owners, because they couldn't keep the cats anymore. Now that being said, we all know that cat breeding is a reality and we can't just stop this. And one of the bad things about breeding is the very fact of inbreeding. This leads to the accumulation of genetic variants that - in parallel to the animals having whatever desired feature - are often also ill. This very much happens with HCM in a variety of breeds and Maine Coons is only one of them. Non-bred "street cats" are usually much more healthy than inbred fancy races, because variety is good!! So why are we suggesting this stretch goal at all? We were asking us following question: Is there something that we - as GENETICISTS - could do that is links cats, health, BUB, and genetics? And our idea is that if we would try to identify mutations that cause HCM in a specific breed, then at least the breeders (that do exist) would be able to breed cats that are more healthy in the future. We don't want to provide knowledge to breed a special fur color, or face or anything. We want to provide knowledge to not breed cats with a heart disease! Finally, you can be sure that your donation will not support this. Our idea for the stretch goal is an independent project and the money we collected up to now only covers the costs of sequencing BUB. That is the current price tag on sequencing a genome and we will use it for nothing else. And I have to emphasize again how incredibly grateful we are for your donation and we can't thank you enough! We truly mean this and I hope that you see our best intentions of proposing the stretch goal that we did. If it's OK for you I would update the above lab note with some of my answers above. Best wishes - daniel
May 20, 2015
The LilBubome - Sequencing LilBub's Magical Genome
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Hey Rhiannon and Anthony. Awesome to get your support. We're already looking forward to get going and keep you up to date.
May 19, 2015
The LilBubome - Sequencing LilBub's Magical Genome
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Hi Julia. Danke und viele Grüße zurück. Hoffe dir geht's gut.
May 19, 2015
The LilBubome - Sequencing LilBub's Magical Genome
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Thank you so much Taimur. We're looking forward to sharing the results.
May 19, 2015
The LilBubome - Sequencing LilBub's Magical Genome
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Hi Patrick, really awesome! Thanks a lot. We're really looking forward to hopefully sequence the genome (fingers crossed we make it till next week). And we know it could turn out to be really tricky to find the causative mutation (given that BUB doesn't have any direct relatives). And for that we're looking forward to share the data with all who know how to help. Best -d
May 18, 2015
The LilBubome - Sequencing LilBub's Magical Genome
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Hi. If grumpy and happy cats really falll into distinct categories BUB really should fall in the happy category :). But it would be really interesting to see whether you can find something in connection with calcium uptake/metabolism or anything else that has to do with bone biology.
May 14, 2015
The LilBubome - Sequencing LilBub's Magical Genome
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Hi Richard. I keep my fingers crossed that you meet your goal!
May 10, 2015
Do fungi exposed to toxic waste produce novel antimicrobial agents?
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Hi Gerben. Thanks, sometimes I'm still a little bewildered how well so many aspects of this project fit together. The science, LilBUB, and most of all I enjoy the good spirit pretty much everyone spreads (which must be the Magic of BUB)!
May 08, 2015
The LilBubome - Sequencing LilBub's Magical Genome
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Thank you Judy (and Ian in the comment above). We're all very very excited and hope we will be able to share also the road to the results with all of you!
May 08, 2015
The LilBubome - Sequencing LilBub's Magical Genome
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That's right. As a backer we're not only forever grateful to you, but you'll be automatically notified whenever we have something new. But you can follow us as well on twitter or facebook. Why not do all at once ;). Thank you so much for your interest!!
May 05, 2015
The LilBubome - Sequencing LilBub's Magical Genome
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