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Sep 21, 2016
Project: Part 2: Can low carbohydrate ketogenic diets inhibit cancers?
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Prof. Fine, what do you think should be the next step in light of these findings?
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Reply to:
Eugene J Fine
Eugene J Finethat should provide fairly sufficient time to see some effects, I assume.
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Gene, do we have an approximate on how long it will last?
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Gene, do you think this could be helpful. It was published just a few days ago: "If you think of ROS as fire, then NADPH is like the water used by cancer cells to douse the flames," Dr. DeBerardinis said. But how could NADPH from the PPP help deal with the stress of ROS produced in a completely d...more
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Dr. Fine, do you think the lower ATP in cancer cells is directly involved in UCP2 overexpression? is the lower ATP correlated with the % AcAc to the medium?
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Gene, the findings seem to be consistent with data that's out there. especially in terms of the correlation between UCP2 and Warburg. I'm sure you are familiar with this study: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024792
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