Eugene J Fine

Eugene J Fine

eugene.fine@einstein.yu.edu

Albert Einstein College of Medicine/Montefiore Medical Center/ SUNY Downstate Medical Center

Professor of Radiology (Nuclear Medicine)

More

Published on Feb 24, 2021

New results part I. Animal studies

We've had some difficulties getting these results posted, but we can try again here. It's now February of 2021 and there's much to report. We've published a mouse study (in PLOS ONE) entitled: "The...

Group 6 Copy 860
Published on Jul 16, 2018

Almost forgot some news

A lovely human and humane documentary out of Australia called "The Magic Pill" has been available on Netflix. We should have mentioned it earlier, but better now than to have forgotten completely.T...

Group 6 Copy 762
Published on Jul 09, 2018

Things are finally moving ahead

Things are finally moving ahead1) In our last lab note, many months ago, we were expecting our human trial to begin very shortly. We finally began our human trial in JUNE 2018, more than 9 months a...

Group 6 Copy 821
Published on Sep 13, 2017

What's happened since we obtained funding?

What's happened since we obtained funding?In case you missed it, we sent a message several months ago that, as an unexpected bonus from our Experiment campaign and your donations, we found an angel...

Group 6 Copy 1,135
Published on Jun 14, 2017

We are very excited to inform you

We want all of you to be aware that we have experienced a breakthrough in support for our research which happened because of you.A philanthropic donor found us on the Experiment.com site. He has si...

Group 6 Copy 2,088
Published on Jan 04, 2017

What you've done for us--Our next steps

Anna and Gene are in front of the newly obtained Microplate reader (blue and white, right behind the diskette that Anna's holding). This was purchased with your donations and now ma...

Group 6 Copy 344
Published on Sep 30, 2016

Where we go from here! (We promised)

We've been enormously gratified by the response of thousands of people to the idea that we may be able to influence our body's metabolism in the direction of improved health by restricting the amo...

Group 6 Copy 245
Published on Sep 27, 2016

Thank you AGAIN! So where do we go from here?

So many of you have told us that you feel part of theresearch process. We have felt the same way. We've had to pinch ourselves when we've contrasted this experience to writing a grant toan imperson...

Group 6 Copy 234
Published on Sep 23, 2016

What did Dr. Owen and Dr. Cahill do? Why was this so important?

In the late 1960's, Drs. Oliver Owen and George Cahill did one of the fundamental experiments in brain metabolism. (Mea culpa-- I identified Dr. Owen as Robert Owen mistakenly, now corrected). They...

Group 6 Copy 3,789
Show more updates
This is true, but the point is that other cancers may respond. It's important to determine which cancers are responsive to a particular therapy in advance of the treatment. In breast cancer, for example, the biopsy specimen can provide information about the expression of estrogen receptors (ERs) on the cancer cells. If they express ERs, the cancer is likely to respond well to ER blockers, such as Tamoxifen. Tamoxifen has revolutionized the treatment of breast cancer for many women. I hope this helps. Gene and Richard.
Apr 01, 2021
Can low carbohydrate ketogenic diets inhibit cancers?
View comment
Yes, it's possible, but the point is that it's also possible for a keto diet to help. What's most important is to determine in advance whether the tumor is likely to respond to the keto diet. This is analogous to breast cancer treatment, where estrogen receptor expression, in advance (from biopsy material), determines whether to use estrogen receptor blockers, such as tamoxifen. I hope this helps. Gene and Richard
Apr 01, 2021
Can low carbohydrate ketogenic diets inhibit cancers?
View comment
Hi Cindy, Thank you so much for your comment and your support. We hope that our results will translate to humans, but that's always the big question. Mice and humans are mammals but that only gets us so far. Gene and Richard
Mar 07, 2021
Part 2: Can low carbohydrate ketogenic diets inhibit cancers?
View comment
We agree completely and believe that keeping insulin low speaks strongly to prevention. Thanks so much for you comments and support. Gene and Richard
Mar 07, 2021
Part 2: Can low carbohydrate ketogenic diets inhibit cancers?
View comment
Thank you so much. I tried to link the study but it didn't work. I wrote to Experiment to ask them about it, but so far they haven't been able to fix it. I don't get it, and it's definitely frustrating. Gene and Richard
Feb 25, 2021
Part 2: Can low carbohydrate ketogenic diets inhibit cancers?
View comment
Than you Rod for staying with us. The research has proceeded slower than we'd hoped, partly due to COVID. Best, Gene and Richard
Feb 25, 2021
Part 2: Can low carbohydrate ketogenic diets inhibit cancers?
View comment
I'm way behind in responding to remarks. Thank you. Gene and Richard
Mar 27, 2019
Part 2: Can low carbohydrate ketogenic diets inhibit cancers?
View comment
Egads. We've been doing a lot of cell studies but we haven't posted them. We have to decide what constitutes "publishing in the press", as we haven't published the data in a journal yet. I'll talk with Richard. I think we can show some of the data. Gene and Richard
Mar 27, 2019
Part 2: Can low carbohydrate ketogenic diets inhibit cancers?
View comment
Hi Ashley, Thank you for your comment. I'm unsure if you meant this as a question, but if so, sure it's sharable. Gene and Richard
Jan 13, 2019
Can low carbohydrate ketogenic diets inhibit cancers?
View comment
Thanks for the additional remarks Steve. We're doing a ketogenic diet cancer study right now, although it can't be described as zero carbohydrates. I'm not sure that even full carnivore is zero carbs in view of muscle glycogen, but I need to refresh my knowledge of the glycogen content in red meat and whether it withstands cooking. Gene and Richard
Sep 24, 2018
Can low carbohydrate ketogenic diets inhibit cancers?
View comment
Dear Steve, That is outstanding news! Interestingly, I suspect that you may have been responsive to a strict ketogenic diet because your prostate cancer was so aggressive. By this I mean that it was so PET avid. Many less aggressive prostate cancers are not glycolytic/glucose-dependent, I.e. can metabolize fatty acids and ketone bodies as fuels. In any event, we wish you continued good health and thank you very much for sharing your news with us!! Best, Gene and Richard
Sep 24, 2018
Can low carbohydrate ketogenic diets inhibit cancers?
View comment
Dear Lech, Thanks so much for your continued interest. We've had difficulties starting our human trial in losing one food vendor, finding another but only from overseas, as we then needed USDA approval to import the foods because we couldn't find a ketogenic food vendor in the U.S. The irony to me was that it would have been easier to do a drug trial. However, we've straightened all these things out and we're expecting a food delivery actually within a week, and can likely start our human trial within another week. So we're eager to start the human trial. The animal trial has also been held up by food issues. We will have more news in about a week on the cell studies. Best, Gene
Mar 11, 2018
Part 2: Can low carbohydrate ketogenic diets inhibit cancers?
View comment
Show more comments