Patrick Frost, PhD

Patrick Frost, PhD

Jan 13, 2016

Group 6 Copy 51
-1
    Please wait...

    About This Project

    BBRI and Los Angeles VA Medical Center

    Multiple myeloma (MM) is a cancer of the bone marrow made up of plasma cells (a type of antibody-producing white blood cells). Low oxygen levels (called hypoxia) in the bone marrow increases gene expression in MM tumor cells as part of an adaptive survival response. We are targeting this hypoxic response with an experimental drug that blocks expression of these genes to ask if this molecule kills MM in the bone marrow. This is a novel approach to treat MM, an incurable disease.

    Blast off!

    Browse Other Projects on Experiment

    Related Projects

    An initial exploration of in-situ underwater genetic sequencing

    Our goal is to adapt portable genome sequencing technology for high-pressure, underwater environments. Currently...

    Round Goby assault on American rivers: How fast, how far, how complete?

    After conquering the Great Lakes, what will the invasive Round Goby do to fish in our streams? Four years...

    Researching 2,000 pound turtles along the Florida coast

    Leatherback sea turtles (Dermochelys coriacea) are the largest species of sea turtle, often reaching over...

    Backer Badge Funded